Results 81 to 90 of about 74,254 (240)
BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer
Advanced Science, EarlyView.BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu +12 more
wiley +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Sexually Transmitted Diseases Determinant among Online Sex Workers in Indonesia
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)Background: Since the beginning of Indonesia’s Reformation era, hundreds of localizations have been closed to control prostitution and human trafficking.
Gabby Gabriela Ginting +2 more
doaj +1 more source
Advanced Science, EarlyView.This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang +10 more
wiley +1 more source
Advanced Science, EarlyView.The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen +10 more
wiley +1 more source
La traducció: l'experiència de traduir .Taula rodona
, 2012 Taula rodona-col·loqui amb ex-alumnes sobre la traducció i l'experiència de traduir els clàssics llatins, en el marc de l'activitat 'Dolors Condom a les Lliçons de la Càtedra M.
Condom i Gratacòs, Dolors
core +3 more sources
[Inconsistent condom use among sexual workers in Ecuador: results from a behavior survey].
, 2006 OBJECTIVE: Whilst existing data suggests that the HIV epidemic in Ecuador is concentrated amongst men who have sex with men (MSM), there is very little available information on the situation of key populations, i.e.
Bertozzi, Stefano Michele +3 more
core +1 more source
Advanced Science, EarlyView.This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang +6 more
wiley +1 more source
Condom-related problems among a racially diverse sample of young men who have sex with men
, 2010 HIV prevalence remains disproportionately high among men who have sex with men (MSM) [1]. Young MSM (YMSM) exhibit particularly high HIV prevalence and are one of the few populations to demonstrate recent increases in their HIV infection rate [1]. Racial
Erin Emerson (7921499) +2 more
core +4 more sources
Promoting the female condom to refugees [PDF]
Forced Migration Review, 2006 UNHCR and its partners have been providing male condoms since the late 1990s. However, uptake remains alarmingly low. Will the agency be more successful in promoting the female condom, a female-initiated barrier method of contraception and disease ...
Jacqueline Papo
doaj