Results 61 to 70 of about 725,143 (289)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The effect of childhood conduct disorder on human capital [PDF]

open access: yes, 2010
This paper estimates the longer-term effects of childhood conduct disorder on human capital accumulation and violent and criminal behaviour later in life using data of Australian twins.
Koning, Pierre   +3 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

ADJUSTMENT PROBLEMS AMONG CHILDREN WITH ATTENTION DEFICIT HYPERACTIVE DISORDER (ADHD) CONDUCT DISORDER (CD)

open access: yesIndian Journal of Psychiatric Nursing, 2016
Attention Deficit Hyperactive Disorder (ADHD) and Conduct disorder (CD) is the most common psychiatric problem diagnosed among children. Present study is undertaken as a cross sectional study of children with ADHD and conduct disorder to identify their ...
Sumity Arora, Uma Joshi, Sandhya Gupta
doaj   +1 more source

Comorbilidad entre trastornos de conducta y depresión mayor en la adolescencia: prevalencia, teorías explicativas y estatus nosológico [PDF]

open access: yes, 2009
This theoretical study examines the main findings and researches regarding the comorbidity between conduct disorder and major depression in adolescence.
Carrasco Tornero, Ángel   +4 more
core   +1 more source

Atypical neural responses to vocal anger in attention-deficit/hyperactivity disorder [PDF]

open access: yes, 2014
Background Deficits in facial emotion processing, reported in attention-deficit/hyperactivity disorder (ADHD), have been linked to both early perceptual and later attentional components of event-related potentials (ERPs).
Banaschewski   +59 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Stroke: Is it sometimes overlooked? [PDF]

open access: yesABC: časopis urgentne medicine, 2017
Introduction Acute stroke is defined as an abrupt focal or global disorder of cerebral function. Ischemic stroke is significantly more frequent than the hemorrhagic stroke (75-80% of all).
Milutinović Vojislava V.   +1 more
doaj  

The New Multi-Ministry Response to Conduct Problems: A SWOT analysis [PDF]

open access: yes, 2008
The Inter-agency Plan for Conduct Disorder/Severe Antisocial Behaviour 2007-2012 (Ministry of Social Development, 2007) is assessed according to the SWOT dimensions of strengths, weaknesses, opportunities and threats.
Stanley, Peter
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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