Results 71 to 80 of about 725,143 (289)

Testing Developmental Pathways to Antisocial Personality Problems [PDF]

, 2009
This study examined the development of antisocial personality problems (APP) in young adulthood from disruptive behaviors and internalizing problems in childhood and adolescence.
Sofia Diamantopoulou, Frank C. Verhulst, Jan van der Ende, CS Abramowitz, TM Achenbach, TM Achenbach, TM Achenbach, American Psychiatric Association, A Angold, T Armstrong, J Biederman, DW Black, IL Bongers, M Brown, JD Burke, JD Burke, BE Compas, WE Copeland, EJ Costello, NR Crick, R Graaf de, B Dolan, BM D’Onofrio, AD Farrell, RF Ferdinand, RF Ferdinand, DM Fergusson, DM Fergusson, E Fombonne, PJ Frick, J Hill, S Hinshaw, S Hodgins, MB Hofstra, LT Hu, PS Jensen, S Kasen, M Kerr, J Kim-Cohen, M Kovacs, L Kratzer, BB Lahey, BB Lahey, SO Lilienfeld, R Loeber, R Loeber, R Loeber, R Loeber, R Loeber, F Lösel, DR Lynam, MT Lynskaey, S Mannuzza, B Maughan, B Maughan, TE Moffitt, MC Monuteaux, P Moran, LK Muthén, M Nock, JM Ostrov, SH Rhee, MF Russo, RT Salekin, A Satorra, JL Schafer, P Silverthorn, AM Sourander, AM Sourander, A Storm-Mathisen, M Timmermans, RE Tremblay, I Meurs Van, JH Westerlaak van, FC Verhulst, FC Verhulst, JJ Washburn, J Westermeyer, NS Whittinger, EG Willcutt   +79 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Some individual psychological characteristics as protective or risk factors for occurrence of conduct disorder [PDF]

Psihologija, 2011
Our study included 30 pairs of siblings aged 12-18 years; one sibling with and one without conduct disorder in each pair. The aim of the study was to assess individual characteristics of those siblings, i.e.
Marković Jasminka, Srdanović-Maraš Jelena, Šobot Valentina, Ivanović-Kovačević Svetlana, Martinović-Mitrović Slađana   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Moral competence and conduct disorder among Filipino children in conflict with the law

Neuropsychopharmacology Reports, 2019
Aims The numbers of children in conflict with the law continue to rise in Asia, yet few studies have been conducted regarding factors associated with it. It has been theorized that children with conduct disorder represent majority of children in conflict
Melissa Paulita V. Mariano
doaj   +1 more source

Understanding mechanisms of genetic risk for adolescent internalizing and externalizing problems: The mediating role of parenting and personality [PDF]

, 2018
Genetic predispositions play an important role in the development of internalizing and externalizing behaviors. Understanding the mechanisms through which genetic risk unfolds to influence these developmental outcomes is critical for developing ...
Bucholz, Kathleen K, Dick, Danielle M, Edenberg, Howard J, I-Chun Kuo, Sally, Kramer, John R, Schuckit, Marc, Su, Jinni   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Does violence solve anything? Conduct disorder as adaptive behaviour

Canadian Journal for New Scholars in Education, 2010
Many teachers and students report that in recent years violence is becoming more prevalent in schools. This paper examines the adaptive component of behaviours associated with a specific disruptive behavioural disorder: conduct disorder.
Rick Nelson Noble
doaj