Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Boys with oppositional defiant disorder/conduct disorder show impaired adaptation during stress: an executive functioning study [PDF]
, 2017 Evidence for problems in executive functioning (EF) in children with oppositional defiant disorder/conduct disorder (ODD/CD) is mixed and the impact stress may have on EF is understudied.
de Wied, Minet +4 more
core +4 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Comorbilidad entre trastornos de conducta y depresión mayor en la adolescencia: prevalencia, teorías explicativas y estatus nosológico [PDF]
, 2009 This theoretical study examines the main findings and researches regarding the comorbidity between conduct disorder and major depression in adolescence.
Carrasco Tornero, Ángel +4 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Moral competence and conduct disorder among Filipino children in conflict with the law
Neuropsychopharmacology Reports, 2019 Aims The numbers of children in conflict with the law continue to rise in Asia, yet few studies have been conducted regarding factors associated with it. It has been theorized that children with conduct disorder represent majority of children in conflict
Melissa Paulita V. Mariano
doaj +1 more source
Some individual psychological characteristics as protective or risk factors for occurrence of conduct disorder [PDF]
Psihologija, 2011 Our study included 30 pairs of siblings aged 12-18 years; one sibling with and one without conduct disorder in each pair. The aim of the study was to assess individual characteristics of those siblings, i.e.
Marković Jasminka +4 more
doaj +1 more source
Differential effect of behavioural strategies on the management of conduct disorder among adolescents in correctional centres in Lagos State, Nigeria [PDF]
, 2015 Adolescent period is a significant phase in human development. Empirical evidences from diverse nations revealed that the period is characterized by a number of misbehaviours of which conduct disorder is paramount.
Alexander Krannich (804286) +5 more
core +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source