Results 81 to 90 of about 725,143 (289)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Boys with oppositional defiant disorder/conduct disorder show impaired adaptation during stress: an executive functioning study [PDF]
, 2017 Evidence for problems in executive functioning (EF) in children with oppositional defiant disorder/conduct disorder (ODD/CD) is mixed and the impact stress may have on EF is understudied.
de Wied, Minet +4 more
core +4 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Evidence based administration of risperidone and paliperidone for the treating conduct disorder
Journal of Research in Medical Sciences, 2013 Background: This study evaluates the evidence-based administration of risperidone and paliperidone for the treating children and adolescents with conduct disorder (CD).
Ahmad Ghanizadeh
doaj
'Glocal' disorder: causes, conduct and consequences of the 2008 Greek unrest [PDF]
, 2016 This article examines the unrest that emanated in Athens and rolled out across Greek cities in December 2008 as a case through which to advance understanding of how local, national and international arenas may together shape localised episodes of ...
Amnesty International +28 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Behavioral Predictors Of Substance-Use Initiation In Adolescents With And Without ADHD
Pediatric Neurology Briefs, 2006 Substance-use initiation was examined in 28 healthy adolescents and 50 with attention-deficit/hyperactivity disorder, followed longitudinally for 4 years at the National Institute of Mental Health, Bethesda, MD; National Institute on Drug Abuse ...
J Gordon Millichap
doaj +1 more source
Couple and family therapies for post-traumatic stress disorder (PTSD) [PDF]
, 2014 This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The objectives of this review will be to: assess the efficacy of couple and family therapies for adult PTSD, relative to 'no treatment' conditions, 'standard care ...
Cowlishaw, Sean +3 more
core +4 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source