Results 151 to 160 of about 11,831,950 (329)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Children's with conduct disorders problem solving in children homes

open access: yes, 2012
Izvēlētā diplomdarba tēma ir „Bērnu ar uzvedības traucējumiem problēmu risinājums bērnu namā”. Izvirzītais diplomdarba mērķis ir pētīt uzvedības traucējumu problēmu risināšanas veidus ilgstošās sociālās aprūpes un sociālās rehabilitācijas institūcijās ...
Degterjova, Ella
core  

A Rating Scale to Differentiate between Conduct Disorder and Attention Deficit Hyperactivity Disorder

open access: yesمجله دانشکده پزشکی اصفهان, 2009
Background: The symptoms of conduct disorder and ADHD (attention deficit hyperactivity disorder) have many overlaps. These two disorders are considered to be the two most common psychiatric disorders among school aged children.
Sayed Jalal Sadrossadat   +5 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Minnesota Multiphasic Personality Inventory-adolescent-restructured Form (MMPI-A-RF): Characteristics of Conduct Disorder [PDF]

open access: yesJournal of Rehabilitation
Objective Disruptive and conduct behaviors are the most common conditions used to help adolescent patients refer to mental health clinics for counseling. The prevalence of this disorder is increasing and it is necessary to concentrate on this topic.
Marzieh Norozpour   +4 more
doaj  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Preliminary data on the prevalence of psychiatric disorders in Brazilian male and female juvenile delinquents

open access: yesBrazilian Journal of Medical and Biological Research, 2004
The aim of the present investigation was to study the prevalence of psychiatric disorders in a sample of delinquent adolescents of both genders and to compare the prevalence between genders. A total of 116 adolescents (99 males and 17 females) aged 12 to
Andrade R.C.   +2 more
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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