Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Psychosocial correlates of recidivism in a sample of ex-prisoners: the role of Oppositional Defiant Disorder and Conduct Disorder [PDF]
The present study aimed to (a) examine the role of Oppositional Defiant Disorder and Conduct Disorder in predicting recidivism, while controlling for childhood arrest, perceived neighbourhood crime frequency, alcohol consumption, age, and gender, and (b)
Dhingra, Katie +7 more
core +1 more source
Family problems associated with conduct disorder perceived by patients, families and professionals
INTRODUCTION: Conduct disorder is among the most serious and complex complications in school-aged children. Considering severe problems in the families of children with conduct disorder, this article aimed to investigate such problems in this group ...
Sajad Sajadi +3 more
doaj +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Psychiatry and politics in Pelotas, Brazil: the equivocal quality of conduct disorder and related diagnoses. [PDF]
The world-wide emergence of categories for diagnosing mental health problems in children and youth such as conduct disorder is often attributed to the globalization of a highly biomedical form of psychiatry.
Béhague, Dominique P. +2 more
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Conduct disorder and somatic health in children: a nationwide genetically sensitive study
Background Conduct disorder (CD), a serious behavioral and emotional disorder in childhood and adolescence, characterized by disruptive behavior and breaking societal rules.
Nóra Kerekes +6 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
AIS Code of Research Conduct [PDF]
The AIS Code of Research Conduct offers guidance in matters directly related to the research and publication of scholarly works, and particularly those in the journals and conference proceedings of the Association for Information Systems (whether ...
AIS Research Conduct Committee,
core +1 more source

