Results 141 to 150 of about 7,267,381 (385)

On irreciprocal conduction [PDF]

open access: yesThe London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 1889
n ...
openaire   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

A relation on the effective conductivity of composites [PDF]

open access: yesarXiv, 2017
Consider a 2D composites with non-overlapping equal inclusions imbedded in a host material of the normalized unit conductivity. The conductivity of inclusions takes two values $\sigma_1$ and $\sigma_2$ with the probabilities $p$ and $1-p$, respectively.
arxiv  

The Springs of Conduct

open access: yesNature, 1886
THIS is a thoughtful and extremely well-written little book on psychology and ethics, regarded from the standpoint of evolution. There is not much in it that is strikingly original; but the material is so well arranged, and the views so lucidly expressed, that the work constitutes a most interesting epitome of modern thought upon the subjects of which ...
openaire   +3 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Recovering a quasilinear conductivity from boundary measurements [PDF]

open access: yesarXiv, 2019
We consider the inverse problem of recovering an isotropic quasilinear conductivity from the Dirichlet-to-Neumann map when the conductivity depends on the solution and its gradient. We show that the conductivity can be recovered on an open subset of small gradients, hence extending a partial result to all real analytic conductivities.
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

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