Results 31 to 40 of about 15,415 (218)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Conduct disorders [PDF]

European Child & Adolescent Psychiatry, 2012
Conduct disorder (CD) is a frequently occurring psychiatric disorder characterized by a persistent pattern of aggressive and non-aggressive rule breaking antisocial behaviours that lead to considerable burden for the patients themselves, their family and society.
Jan K. Buitelaar, Kirsten C. Smeets, Pierre Herpers, Floor Scheepers, Jeffrey Glennon, Nanda N. J. Rommelse   +5 more
openaire   +2 more sources

Molecular dynamics simulations highlight structural and functional alterations in deafness–related M34T mutation of connexin 26

Frontiers in Physiology, 2014
Mutations of the GJB2 gene encoding the connexin 26 (Cx26) gap junction protein, which is widelyexpressed in the inner ear, are the primary cause of hereditary non–syndromic hearing loss in severalpopulations.
Francesco eZonta, Damiano eBuratto, Chiara eCassini, Mario eBortolozzi, Mario eBortolozzi, Fabio eMammano, Fabio eMammano, Fabio eMammano   +7 more
doaj   +1 more source

Estimating Precipitating Energy Flux, Average Energy, and Hall Auroral Conductance From THEMIS All-Sky-Imagers With Focus on Mesoscales

Frontiers in Physics, 2021
Recent attention has been given to mesoscale phenomena across geospace (∼10 s km to 500 km in the ionosphere or ∼0.5 RE to several RE in the magnetosphere), as their contributions to the system global response are important yet remain uncharacterized ...
Christine Gabrielse, Toshi Nishimura, Margaret Chen, James H. Hecht, Stephen R. Kaeppler, D. Megan Gillies, Ashton S. Reimer, Larry R. Lyons, Yue Deng, Eric Donovan, J. Scott Evans   +10 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The Conduct of a Review

Australasian Journal of Information Systems, 2016
Editorial ...
John W Lamp, Oliver K Burmeister
openaire   +3 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Do seasonal changes in Svalbard reindeer fur have relevance for heat transfer?

Rangifer, 2002
Physical characteristics of Svalbard reindeer (Rangifer tarandus platyrhynchus) fur samples were examined with respect to season. A total of 33 dorsal fur sections including adults and calves were investigated.
Christine Cuyler, Nils A. Øritsland
doaj   +1 more source