Results 71 to 80 of about 1,557,902 (292)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Conducting polymer actuators: from basic concepts to proprioceptive systems [PDF]

open access: yes, 2015
[SPA] Esta tesis doctoral se presenta bajo la modalidad de compendio de publicaciones. Es apoyado por 12 documentos, de los 27 en coautoría del candidato y publicados en diferentes revistas durante el desarrollo de esta tesis.
Martínez Gil, José Gabriel
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Electrical properties and vapour sensing characteristics of a novel metal-polymer composite [PDF]

open access: yes, 2008
Quantum Tunnelling Composite (QTC) is a metal polymer composite, commercialised and produced using a patented manufacture process. This process ensures that the metal particles within an elastomerie polymer matrix maintain a highly fractal surface ...
Graham, Adam
core  

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

open access: yesAdvanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora   +4 more
wiley   +1 more source

Changes in articular cartilage after meniscectomy and meniscus replacement using a biodegradable porous polymer implant [PDF]

open access: yes, 2010
Purpose: To evaluate the long-term effects of implantation of a biodegradable polymer meniscus implant on articular cartilage degeneration and compare this to articular cartilage degeneration after meniscectomy.
Arend Jan Schouten   +17 more
core   +6 more sources

Low‐Temperature Imidization of Polyimides (PI) for Scalable Manufacturing of Flexible Wearable Electronics

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐temperature imidization of PEG‐modified polyimide enables fully screen‐printed, roll‐to‐roll fabrication of flexible electrodes on PET substrates, delivering robust mechanical durability and reliable ECG/EMG signal performance for wearable electronics.
Akib Abdullah Khan, Jong‐Hoon Kim
wiley   +1 more source

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

open access: yes, 2022
Today, nanomedicine seeks to develop new polymer composites to overcome current problems in diagnosing and treating common diseases, especially cancer.
Navid Omidifar   +17 more
core   +1 more source

A Water-Dispersible Quinoid-Resonant Conducting Polymer for Organic Electronics

open access: yesOrganic Materials, 2020
Developing stable and solution-processable highly conductive polymers has been the research goal in organic electronics since the first demonstration of metallic conductive polyacetylene.
Dafei Yuan, Xiaozhang Zhu
doaj   +1 more source

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