Results 191 to 200 of about 1,088,283 (304)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Transient conduction block of the superior vena cava following pulsed field ablation of the right superior pulmonary vein. [PDF]

J Arrhythm
Takahashi K, Makita T, Shimoshige S, Kuwahara T.   +3 more
europepmc   +1 more source

XXIX. On the conduction of electricity through gases between parallel plates [PDF]

, 1905
Alfred A. Robb
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

An in silico guide for ventriculo-ventricular delay programming for left bundle branch-optimized cardiac resynchronization therapy. [PDF]

Europace
Strocchi M, Samways JW, Naraen A, Ali N, Shun-Shin MJ, Gillette K, Rinaldi CA, Arnold AD, Plank G, Vigmond EJ, Whinnett ZI, Niederer SA.   +11 more
europepmc   +1 more source

9. On the Excitation-conduction Gradient in the Unfertilized Egg of the Lamprey, Lampetra planeri

, 1944
Toki‐O Yamamoto
openalex   +2 more sources

XLIX. On the action of the solvent in electrolytic conduction [PDF]

, 1887
T.C. Fitzpatrick
openalex   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

On Heat Conduction in Highly Rarefied Air 1 [PDF]

, 1881

openalex   +1 more source