Results 221 to 230 of about 552,451 (296)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Substrate-Dependent Pro- and Antiarrhythmic Action of Omecamtiv Mecarbil at the Ventricular and Atrial Level: Insights from a Langendorff-Perfused Rabbit Heart Model. [PDF]

Cardiovasc Toxicol
Wolfes J, Neff K, Wegner F, Rath B, Doldi F, Eckardt L, Frommeyer G, Ellermann C.   +7 more
europepmc   +1 more source

Electrophysiology of the Camel Heart: A Systematic Review of Evidence from <i>Camelus dromedarius</i>. [PDF]

Biology (Basel)
Alshamsi A, Abdulhakim J, Alnuaimi M, Rahma AT, AlSheryani R, Elkonaisi I, Howarth FC.   +6 more
europepmc   +1 more source

Alternating bundle branch block and infra-Hisian Mobitz II block: an educational case of rapidly progressive His-Purkinje disease. [PDF]

Eur Heart J Case Rep
Hernandez S, Isber R, Bhanushali K, Fahed J, Isber N.   +4 more
europepmc   +1 more source