Results 81 to 90 of about 1,088,283 (304)
On propose une étude numérique, par différences finies, du transfert de chaleur dans un mur multicouche (à deux ou trois couches) soumis à une condition de rayonnement solaire sur le côté extérieur et prenant en compte les échanges de chaleur par ...
Y. Tamene, S. Abboudi, C. Bougriou
doaj
Cold Fronts and Gas Sloshing in Galaxy Clusters with Anisotropic Thermal Conduction
(Abridged) Cold fronts in cluster cool cores should be erased on short timescales by thermal conduction, unless protected by magnetic fields that are "draped" parallel to the front surfaces, suppressing conduction perpendicular to the fronts.
Lee, D.+3 more
core +1 more source
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring+6 more
wiley +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Information filtering via biased heat conduction
Heat conduction process has recently found its application in personalized recommendation [T. Zhou \emph{et al.}, PNAS 107, 4511 (2010)], which is of high diversity but low accuracy.
J. Bennett+5 more
core +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
What is the arrhythmic substrate in viral myocarditis? Insights from clinical and animal studies
Sudden cardiac death (SCD) remains an unsolved problem in the 21st century. It is often due to rapid onset, ventricular arrhythmias caused by a number of different clinical conditions.
Gary Tse+5 more
doaj +1 more source
Breakdown of the interlayer coherence in twisted bilayer graphene
Coherent motion of the electrons in the Bloch states is one of the fundamental concepts of the charge conduction in solid state physics. In layered materials, however, such a condition often breaks down for the interlayer conduction, when the interlayer ...
Dong Chul Kim+12 more
core +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source