Towards Real-World Applications of Personalized Anesthesia Using Policy Constraint Q Learning for Propofol Infusion Control [PDF]
, 2023 Automated anesthesia promises to enable more precise and personalized anesthetic administration and free anesthesiologists from repetitive tasks, allowing them to focus on the most critical aspects of a patient's surgical care. Current research has typically focused on creating simulated environments from which agents can learn.
arxiv +1 more source
Postoperative atrial fibrillation: The role of the inflammatory response [PDF]
, 2017 OBJECTIVE: Abnormal atrial conduction has been shown to be a substrate for postoperative atrial fibrillation (POAF). This study aimed to determine the relationship between the location of the atrial reentry responsible for POAF, and degree of atrial ...
Damiano, Ralph J +4 more
core +2 more sources
Ilioinguinal and Iliohypogastric Nerve Blocks in Children
Central Asian Journal of Medical Sciences, 2017 Objectives: To examine ilioinguinal and iliohypogastric (ILIH) nerve block techniques among children. Methods: A total of 120 children, aged 1-16 years, were included in this prospective, randomized, single-blinded study.
Odgerel Boldbaatar +4 more
doaj +1 more source
A Model-Based Architecture for Automatic Anesthesia Infusion [PDF]
arXiv, 2021 This paper presents a model-based control architecture. Based on the Medical Cyber-physical Systems (MCPS) concept, we construct a safe and reliable automatic anesthesia control closed-loop system. The control architecture uses the patient's propofol pharmacokinetic/pharmacodynamic model, using the calculated results as a feedback signal to correct the
arxiv
The thermodynamics of general anesthesia [PDF]
Biophys. J. 92 (2007) 3159-3165, 2006 It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
arxiv +1 more source
Radical pairs may play a role in xenon-induced general anesthesia [PDF]
Sci Rep 11, 6287 (2021), 2020 Understanding the mechanisms underlying general anesthesia would be a key step towards understanding consciousness. The process of xenon-induced general anesthesia has been shown to involve electron transfer, and the potency of xenon as a general anesthetic exhibits isotopic dependence. We propose that these observations can be explained by a mechanism
arxiv +1 more source
Comparison of dexmedetomidine and opioids as local anesthetic adjuvants in patient controlled epidural analgesia: a meta-analysis [PDF]
Korean Journal of AnesthesiologyBackground Data on the efficacy and incidence of adverse effects associated with dexmedetomidine (DEX) as a local anesthetic adjuvant for patient-controlled epidural analgesia (PCEA) are inconclusive. This meta-analysis assessed the efficacy and risks of
Yafen Gao +4 more
doaj +1 more source
Population pharmacokinetics of levobupivacaine during a transversus abdominis plane block in children [PDF]
Therapeutic Drug Monitoring, Lippincott, Williams & Wilkins, 2019,
pp.1, 2019 BACKGROUND:Levobupivacaine is commonly used during transversus abdominis plane block in pediatric patients. However, the dosing regimen is still empirical, and the pharmacokinetic properties of levobupivacaine are not considered. Here, the pharmacokinetics of levobupivacaine during an ultrasound-guided transversus abdominis plane block were evaluated ...
arxiv +1 more source
Comparison of the median and intermediate approaches to the ultrasound-guided sacral erector spinae plane block: a cadaveric and radiologic study [PDF]
Korean Journal of AnesthesiologyBackground Erector spinae plane block (ESPB) is a well-established method for managing postoperative and chronic pain. ESPB applications for the sacral area procedures are called sacral ESPBs (SESPBs).
Bilge Olgun Keleş +7 more
doaj +1 more source
The significance of widely split P waves: a case report
Journal of Medical Case Reports, 2022 Background P wave morphology on electrocardiogram is often overlooked but indicates abnormal cardiac conduction from various etiologies. Split P waves on electrocardiogram have been reported previously but not in a perioperative setting.
Marianne C. Chen, Jay B. Brodsky
doaj +1 more source