Results 71 to 80 of about 856,405 (365)

General anesthesia or conscious sedation in paroxysmal atrial fibrillation catheter ablation

Biomedical Papers, 2021
Background. Catheter ablation of paroxysmal atrial fibrillation (AF) can be performed under general anesthesia or conscious sedation. The influence of type of anesthesiology care on procedural characteristics and ablation outcome in patients in whom ...
Ondrej Moravec, Tomas Skala, Olga Klementova, Jitka Skalova, Martin Hutyra, Jan Precek, Marian Fedorco, Vlastimil Cernicek, Zbynek Tudos, Jana Zapletalova, Milos Taborsky   +10 more
doaj   +1 more source

The effects of repetitive electric cardiac stimulation in dogs with normal hearts, complete heart block and experimental cardiac arrest [PDF]

, 1955
Direct cardiac stimulation was conducted in the open chest. In normal animals, auricular stimulation at frequencies faster than the spontaneous rate caused little change in vascular pressures or cardiac output.
GAERTNER, RA, STARZL, TE, WEBB, RC
core   +1 more source

Reduced neural activity during volatile anesthesia compared to TIVA: evidence from a novel EEG signal processing analysis [PDF]

arXiv, 2020
Post-operative cognitive decline is a well-known phenomenon and of crucial importance especially in the elderly. General anesthesia can be accomplished by inhalation-based (volatile) or total intravenous anesthesia (TIVA). While their effects on post-operative symptoms have been investigated, little is known about their influence on brain ...
arxiv  

Stabilizing membrane domains antagonizes n-alcohol anesthesia [PDF]

Biophysical Journal, Volume 111, Issue 3, 9 August 2016, Pages 537-545, 2016
Diverse molecules induce general anesthesia with potency strongly correlated both with their hydrophobicity and their effects on certain ion channels. We recently observed that several n-alcohol anesthetics inhibit heterogeneity in plasma membrane derived vesicles by lowering the critical temperature ($T_c$) for phase separation.
arxiv   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Intravenous infusion of magnesium sulfate and its effect on horses with trigeminal-mediated headshaking. [PDF]

, 2019
BackgroundTrigeminal-mediated headshaking results from low-threshold firing of the trigeminal nerve resulting in apparent facial pain. Magnesium may have neuroprotective effects on nerve firing that potentially dampen signs of neuropathic pain.
Aleman, Monica, Costa, Lais Rosa R, Howey, Quinn, Madigan, John E, Santoyo, Ana C, Sheldon, Shara A   +5 more
core   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms. [PDF]

, 2015
Cardiac dysfunction is a prominent cause of mortality in myotonic dystrophy I (DM1), a disease where expanded CUG repeats bind and disable the muscleblind-like family of splice regulators.
Choi, Jongkyu, Comai, Lucio, Dixon, Donald M, El-Ghazali, Ayea, Fishbein, Michael C, Jordan, Maria C, Park, Sun Young, Reddy, Sita, Roos, Kenneth P   +8 more
core  

The thermodynamics of general and local anesthesia [PDF]

, 2014
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase.
Graesboll, Kaare, Heimburg, Thomas, Sasse-Middelhoff, Henrike   +2 more
core   +2 more sources

Hysteresis in anesthesia and recovery: Experimental observation and dynamical mechanism [PDF]

arXiv, 2020
The dynamical mechanism underlying the processes of anesthesia-induced loss of consciousness and recovery is key to gaining insights into the working of the nervous system. Previous experiments revealed an asymmetry between neural signals during the anesthesia and recovery processes.
arxiv