Results 81 to 90 of about 145,387 (305)

Conductive Hearing Loss and Bone Conduction Devices: Restored Binaural Hearing? [PDF]

, 2011
An important aspect of binaural hearing is the proper detection of interaural sound level differences and interaural timing differences. Assessments of binaural hearing were made in patients with acquired unilateral conductive hearing loss (UCHL, n = 11) or congenital UCHL (n = 10) after unilateral application of a bone conduction device (BCD), and in ...
Agterberg, M.J.H., Hol, M.K.S., Cremers, C.W.R.J., Mylanus, E.A.M., Opstal, A.J. van, Snik, A.F.M.   +5 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

High step up DC–DC converter with low conduction losses and reduced switching losses

IET Renewable Power Generation
This article presents a novel high step up converter based on the active switch inductor (ASL) technique for renewable energy source applications. The coupled inductor technique provides an opportunity to increase the gain.
Zahra Akhlaghi, Amirhossein Karimi, Ehsan Adib   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

INSULATED GATE BIPOLAR TRANSISTOR TEMPERATURE CALCULATION USING SIMSCAPE/SIMULINK ENVIRONMENT WITH VARIOUS SWITCHING FREQUENCY

Journal of Engineering and Sustainable Development
Because of developments in high-power converters, it has become crucial to investigate how effective inverter performance is. consequently, via being aware of the temperature value of the junction for the inverter switch.
Ahmed Shihab Ahmed, Riyadh Ghanim Omar
doaj   +1 more source

High-Efficiency Design and Control of Zeta Inverter for Single-Phase Grid-Connected Applications

Energies, 2019
The conventional zeta inverter has been used for single-phase grid-connected applications. However, it has high switching losses to operate at high switching frequency in the continuous conduction mode (CCM). To address this drawback, this paper suggests
Woo-Young Choi, Min-Kwon Yang
doaj   +1 more source

Efficient solution of the DC-link hard switching inverter of the PV system

Journal of King Saud University: Engineering Sciences, 2020
Soft switching inverter alleviate and treat the negative impacts resulted from hard switching inverter. It provides many advantages such as low power losses, high efficiency, stress reduction during switching instants, and high reliability and lowering ...
Usama Khaled, Hassan Farh, Salman Alissa, Abdulrhman Abanmi, Omar Aldraimli   +4 more
doaj   +1 more source

Active power losses distribution methods for the modular multilevel converter [PDF]

, 2016
Modular Converters such as the MMC have become the new standard in VSC-HVDC applications. Their modularity has brought many industrial advantages but also increased the complexity of their operation.
Merlin, MMC, Mitcheson, PD
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source