Results 41 to 50 of about 23,210,949 (362)

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Genome-wide association studies have identified common noncoding variants associated with ECG parameters in the TBX3 locus, suggesting that a modest change in TBX3/Tbx3 expression level affects heart function. We characterized the morphology,
Rajiv A. Mohan, Fernanda M. Bosada, J. H. van Weerd, K. van Duijvenboden, Jianan Wang, Mathilda T. M. Mommersteeg, Ingeborg B. Hooijkaas, Vincent Wakker, C. de Gier-de Vries, R. Coronel, G. J. Boink, J. Bakkers, P. Barnett, B. Boukens, V. Christoffels   +14 more
semanticscholar   +1 more source

Conduction System Pacing for Cardiac Resynchronization Therapy

Journal of Cardiovascular Development and Disease, 2023
Cardiac resynchronization therapy (CRT) via biventricular pacing (BiVP-CRT) is considered a mainstay treatment for symptomatic heart failure patients with reduced ejection fraction and wide QRS. However, up to one-third of patients receiving BiVP-CRT are
Óscar Cano, Javier Navarrete-Navarro, Pablo Jover, Joaquín Osca, Maite Izquierdo, Josep Navarro, Hebert D. Ayala, Luis Martínez-Dolz   +7 more
doaj   +1 more source

Transcriptional Patterning of the Ventricular Cardiac Conduction System

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: The heartbeat is organized by the cardiac conduction system (CCS), a specialized network of cardiomyocytes. Patterning of the CCS into atrial node versus ventricular conduction system (VCS)
Ozanna Burnicka-Turek, M. Broman, Jeffrey D. Steimle, B. Boukens, N. Petrenko, Kohta Ikegami, Rangarajan D. Nadadur, Y. Qiao, D. Arnolds, X. Yang, V. Patel, Marcelo Araujo da Nóbrega, I. Efimov, I. Moskowitz   +13 more
semanticscholar   +1 more source

Effects of Synaptic and Myelin Plasticity on Learning in a Network of Kuramoto Phase Oscillators [PDF]

, 2019
Models of learning typically focus on synaptic plasticity. However, learning is the result of both synaptic and myelin plasticity. Specifically, synaptic changes often co-occur and interact with myelin changes, leading to complex dynamic interactions ...
D. Dibenedetto, Haken H., Hebb D. O., Kuramoto Y., M. Karimian, M. Moerel, M. Senden, P. De Weerd, Pikovsky A., R. L. Westra, T. Burwick   +10 more
core   +2 more sources

Evolution of the Sinus Venosus from Fish to Human

Journal of Cardiovascular Development and Disease, 2014
The sinus venosus, the cardiac chamber upstream of the (right) atrium, is a severely underinvestigated structure. Yet, its myocardium harbors the cardiac pacemaker in all vertebrates.
Bjarke Jensen, Bastiaan J. D. Boukens, Tobias Wang, Antoon F. M. Moorman, Vincent M. Christoffels   +4 more
doaj   +1 more source

Intracardiac electrophysiological conduction parameters in adult dogs

Veterinary Quarterly, 2017
Background: Invasive electrophysiology study (EPS) is one of the most important adjunct tests for the evaluation of arrhythmias in human medicine. However, EPS is neither well known nor widely used in veterinary medicine.
Alicja Cepiel, Agnieszka Noszczyk-Nowak, Robert Pasławski, Adrian Janiszewski, Urszula Pasławska   +4 more
doaj   +1 more source

Specialized impulse conduction pathway in the alligator heart

eLife, 2018
Mammals and birds have a specialized cardiac atrioventricular conduction system enabling rapid activation of both ventricles. This system may have evolved together with high heart rates to support their endothermic state (warm-bloodedness) and is ...
Bjarke Jensen, Bastiaan J Boukens, Dane A Crossley II, Justin Conner, Rajiv A Mohan, Karel van Duijvenboden, Alex V Postma, Christopher R Gloschat, Ruth M Elsey, David Sedmera, Igor R Efimov, Vincent M Christoffels   +11 more
doaj   +1 more source

Left bundle branch pacing in a 4-year-old patient with complete heart block after correction of transposition of the great arteries via a dual chamber pacing system: a case report

Frontiers in Cardiovascular Medicine
Conduction system pacing is a recently developed pacing modality that serves as an alternative approach in maintaining or restoring physiological ventricular activity. Left bundle branch pacing (LBBP) has been rarely performed in children due to concerns
Omar Fakhreddine, Patrick Sarkis, Jamil Francis, Bernard Abi-Saleh   +3 more
doaj   +1 more source

Conduction system pacing in adults with congenital heart disease

International Journal of Cardiology Congenital Heart Disease, 2021
Conduction system pacing is a growing sub-speciality within electrophysiology and its use is expanding. We conduct a review of the current state of knowledge, evidence and future direction for conduction system pacing in adult congenital heart disease.
Matthew O'Connor, Michael Gatzoulis, Tom Wong   +2 more
doaj   +1 more source

Entropy and Entropy Production in Some Applications

, 2013
By using entropy and entropy production, we calculate the steady flux of some phenomena. The method we use is a competition method, $S_S/\tau+\sigma={\it maximum}$, where $S_S$ is system entropy, $\sigma$ is entropy production and $\tau$ is microscopic ...
Beretta, Casas-Vazquez, Criado-Sancho, Dewar, Dorfman, Kittel, Lebon, Marconi, Martyushev, Mehrer, Paltridge, Yong-Jun Zhang, Zhang, Zhang, Zhang, Ziegler   +15 more
core   +1 more source