Results 51 to 60 of about 602,367 (298)

Conductive Nanofibrous Scaffolds for Tissue Engineering Applications: A Review [PDF]

علوم و تکنولوژی پلیمر, 2019
Designing a biocompatible scaffold that mimics the mechanical, electrical, chemical, and topographical properties of extracellular matrix of the target tissue is one of the main challenges in regulating cellular behaviors.
Zohreh Daraei Nejad, Iman Shabani
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Conductive polymers as electrochemical investigation for enhanced supercapacitor performance: Review [PDF]

Modern Electronic Materials
This review explores the role of conductive polymers in enhancing the performance of electrochemical supercapacitors, a promising solution for sustainable energy storage.
M. Vanitha Sri, V. T. Jeielayaganga, D. Sakthilatha   +2 more
doaj   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Misturas físicas de polipropileno com aditivos condutores: obtenção, caracterização e aplicação para blindagem eletromagnética [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência e Engenharia de MateriaisMisturas poliméricas condutoras de eletricidade, à base de polipropileno (PP) aditivado com negro de ...
Martins, Nilda
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Enhancement of Proton Transport in an Oriented Polypeptide Thin Film [PDF]

, 2013
Proton transport properties of a partially protonated poly(aspartic acid)/sodium polyaspartate (P-Asp) were investigated. A remarkable enhancement of proton conductivity has been achieved in the thin film. Proton conductivity of 60-nm-thick thin film
Matsui, Jun, Miyashita, Tokuji, Yugami, Hiroo, Nagao, Yuki, Hiramatsu, Hirotsugu, Hitoshi Yamamoto, Tokuji Miyashita, Hirotsugu Hiramatsu, Hiroo Yugami, Yuki Nagao, Takashi Abe, Yamamoto, Hitoshi, Abe, Takashi, Noriko Sata, Sata, Noriko, Jun Matsui   +15 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

μSR of conducting and non-conducting polymers

Physica B: Condensed Matter, 2000
Abstract μSR has been used to study a variety of polymers with very different electronic properties. In conducting polymers, the muon-generated radical states take the form of highly mobile polarons. Muon spin relaxation has been used to study the mobility of these polarons and to measure the temperature dependence of their intra-chain and inter ...
Pratt, F.L., Blundell, S.J., Jestädt, Th., Lovett, B.W., Husmann, A., Marshall, I.M., Hayes, W., Monkman, A., Watanabe, I., Nagamine, K., Martin, R.E., Holmes, A.B.   +11 more
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source