Results 191 to 200 of about 1,555,324 (348)

Radiation-induced thermal conductivity degradation in LiAlO₂ and LiAl₅O₈ investigated by molecular dynamics. [PDF]

Sci Rep
Roy A, Casella AM, Devanathan R, Soulami A, Senor DJ.   +4 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Using Biopolymers to Control Hydraulic Degradation of Natural Expansive-Clay Liners Due to Fines Migration: Long-Term Performance. [PDF]

Polymers (Basel)
Al-Mahbashi AM, Shaker A, Almajed A.
europepmc   +1 more source

Validation of cylindrical pavement specimen thermal conductivity protocol

, 2013
Haotian Bai
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Thermoelectric properties of M2BS2 (M = Ti, Zr, Hf) monolayers: An Ab initio study. [PDF]

PLoS One
Wang S, Chen L, Song J.
europepmc   +1 more source

Tillage and wheel traffic effect on hydraulic conductivity

, 1987
Syed Hasan Ali Rizvi
openalex   +2 more sources

Cr-based second phases in a high conductivity Cu-Cr-Nb alloy with high high-temperature strength

, 2022
Yihai Yang, Qian Lei, Huan Liu, Jianda Hong, Zhen Han, Qi An, Jimin Shan, Xi Chen, Haoran Xu, Zhu Xiao, Shen Gong   +10 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Improving the Thermal Conductivity by Varying the Filler Geometry of Copper in Thermosets. [PDF]

Polymers (Basel)
Rösel U, Drummer D.
europepmc   +1 more source