Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Uncovering Structure-Conductivity Relationships in Anion Exchange Membranes (AEMs) Using Interpretable Machine Learning. [PDF]
Naghshnejad P +4 more
europepmc +1 more source
Conductivity sum rules for the relativistic two component plasma
Kenneth I. Golden
openalex +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
High-power laser powder bed fusion of pure copper for simultaneous achievement of high density and electrical conductivity. [PDF]
Oh WJ, Son Y, Kim DH, Kim CS.
europepmc +1 more source
Surface Exchange and Bulk Diffusivity of LSCF as SOFC Cathode: Electrical Conductivity Relaxation and Isotope Exchange Characterizations [PDF]
Yihong Li +3 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Evaluating and improving biocompatibility of conductive polymers for cardiac tissue engineering. [PDF]
Aboagye J +4 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

