Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Flexible MXene nanosheet/multiwall carbon nanotube-reinforced poly (vinylidene fluoride-hexafluoropropylene)-polymethyl methacrylate composites for energy storage and EMI shielding. [PDF]
RSC AdvNath NK +5 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Influence of molecular water dynamics on the electrical conductivity of hydrothermally synthesized hydroxyapatite from cuttlefish bone. [PDF]
RSC AdvChaari M, Megdiche M, Arous M.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hexagonal Boron Nitride Nanosheets: Properties, Preparation and Applications in Thermal Management. [PDF]
Nanomaterials (Basel)Liu M, Wang Y.
europepmc +1 more source
Conductive materials. Conductive graphite materials.
NIPPON GOMU KYOKAISHI, 1988 openaire +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Predicting of tunneling conductivity for polymer-carbon black nanocomposites by interphase percolation. [PDF]
Sci RepBoomhendi M, Vatani M, Zare Y.
europepmc +1 more source