Results 111 to 120 of about 1,342,403 (297)

Automated thermal conductivity probe, and applications to powders [PDF]

open access: yes, 1983
A thermal conductivity probe has been developed for measurements of powders and porous media from ambient temperature to 1300 K in vacuum or an inert gas atmosphere.
Drotning, W D
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Summary of Geoscience's design studies for the rod heat flux transducer and the thermal conductivity probe

open access: yes, 1977
Structural strength calculations are presented for a rod heat flux transducer, thermal conductivity probe, and cable and electrical connectors.
Poppendiek, H. F.   +3 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

An automated probe for thermal conductivity measurements

open access: yes, 1987
A transient technique was validated for making thermal conductivity measurements. The technique incorporated a small, effectively spherical, heat source and temperature sensing probe. The actual thermal conductivity measurements lasted 30 seconds.
Dougherty, Brian P.
core  

Control of bilayer polyelectrolyte coating parameters using the Kelvin probe microscopy [PDF]

open access: yes, 2017
В работе исследовалось бислойное покрытие полиэтиленимин/глюкозооксидаза на поверхности Si/SiO2 методом Кельвин-зонд силовой микроскопии (КЗСМ). При помощи КЗСМ удалось определить влияние освещения и типа проводимости Si на количество адсорбированных ...
Kozlowski, A. V.   +3 more
core  

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