Results 181 to 190 of about 151,867 (307)

Liquid Metal Electrodes: Material Properties, Interfacial Behavior, Fabrication, Performance, and Applications. [PDF]

Micromachines (Basel)
Wu G, Wang G, Han J, Liu Z, Chen C, Li R, Li C, Li W, Gao L.   +8 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Thefts

La imagen contiene una noticia sobre robos en Bogotá, mencionando un intento de robo en la casa del cónsul británico, Henderson. También destaca la organización estructurada de los ladrones y las medidas tomadas para prevenir futuros incidentes.
El Conductor
core  

A Superstrong and Ultratough Stretchable Electronic Conductor With Ultradurable Strain-Insensitive Electromechanical Performance. [PDF]

Adv Sci (Weinh)
Shan Y, Lei D, Huang C, Gong C, Zhang J, Liu X.   +5 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

An Ultra-Compact ARCL-Based MEMS Radar Filter for Mobile Robotic Platforms. [PDF]

Micromachines (Basel)
Ding Y, Zhang R, Fan X, Chen W, Yang Z.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Mr. Driver editor

La imagen contiene una noticia acerca de que el 4 de agosto se asistió a la sala de la universidad central de Bogotá en donde se examinaba al joven Dr. Climaco Ordoñez, en legislación universal y derecho constitucional.
El Conductor
core  

Strain resilient and self-healing nanocomposite conductors with ultralow sheet resistance. [PDF]

Nat Commun
Hou KX, Yu B, Qian Z, Chen ZJ, Qiu PF, Sasaki K, Ju L, Zhang C, Lu WB, Someya T, Yokota T, Li CH.   +11 more
europepmc   +1 more source