Results 41 to 50 of about 826,158 (229)

Condylar Asymmetry in Patients with Unilateral Mandibular Second Premolar Agenesis [PDF]

open access: yes, 2012
Aim:To investigate the condylar and ramal vertical asymmetry in patients with unilateral mandibular second premolar agenesis.Subjects and Methods:Study group included 58 patients (25 female, 33 males) with unilateral mandibular second premolar agenesis ...
Mehmet Bayram   +3 more
core   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

The Bıomechanıcs- Relatıon Between Incısor And Condylar Guıdances In Deep Bıte Cases

open access: yesTurkish Journal of Orthodontics, 1998
The aim of this study was to investigate the biomechanical relationship between the condylar and anterior guidances of patients with symptomatic temporomandibular disorders before and after orthodontic treatment.
Müfide Dinçer   +2 more
doaj   +1 more source

Static mandibular condyle positions studied by MRI and condylar position indicator

open access: yesScientific Reports, 2022
We compared mandibular condyle positions as determined by magnetic resonance imaging (MRI) and a mechanical device, the condylar position indicator (CPI).
Josef Freudenthaler   +4 more
doaj   +1 more source

Reimagining career guidance: towards a pluralistic perspective [PDF]

open access: yes, 2015
Difficulties concerning the identified mis-match between supply and demand sides of the labour market are discussed. The variability of career guidance services for young people across Europe is illustrated together with policy initiatives in some cases ...
Beven, Peter
core  

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

open access: yesAdvanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan   +12 more
wiley   +1 more source

Histogenesis of mandibular condylar cartilage in mice [PDF]

open access: yes, 2008
P(論文)Mandibular condylar cartilage is a member of temporo-mandibular joint and function both as growth and articular cartilage. Developmentally, mandibular condylar cartilage is classified as being the secondary cartilage, differing from primary ...
柴田, 俊一   +3 more
core  

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