Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor +7 more
wiley +1 more source
Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T: regional values, longitudinal repeatability and method agreement. [PDF]
Delattre BMA +8 more
europepmc +1 more source
Similar locomotor patterns across Quarter Horse disciplines inform lameness assessment
Abstract Background Lineage‐based selection is central to the Quarter Horse industry and is often justified by the assumption that morphology determines locomotor function. However, objective evidence linking static conformation to discipline‐specific locomotor behaviour under standardised conditions remains limited.
Renata Farinelli de Siqueira +4 more
wiley +1 more source
High prevalence of generalized ligamentous laxity in patellar dislocation with posterior weight-bearing lateral femoral condyle osteochondral fractures: an observational study and treatment outcomes. [PDF]
Nian Z +8 more
europepmc +1 more source
Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue +14 more
wiley +1 more source
Temporary Fusionless Occipitocervical Fixation of Bilateral Occipital Condylar Avulsion Fractures in an Adult. [PDF]
Rodriguez G +3 more
europepmc +1 more source
Detection of bifid mandibular condyle by panoramic radiography and cone\nbeam computed tomography
Frederico Sampaio Neves +5 more
openalex +2 more sources
Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang +3 more
wiley +1 more source
Case Report: Three-dimensional planning for autologous osteoperiosteal transplantation in the treatment of a massive osteochondral defect of the medial femoral condyle. [PDF]
Xia Y +6 more
europepmc +1 more source

