Results 31 to 40 of about 460,798 (307)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

A study to measure the utility of an AI-enhanced reporting tool in assisting busy CCTA readers with REPORT generation (SMART-REPORT)

BMC Medical Imaging
Purpose This study aimed to determine if an integrated structured reporting (SR) tool incorporating results from artificial intelligence (AI) enabled coronary stenosis quantification (AI-CSQ), AI-enabled coronary plaque analysis (AI-CPA), and fractional ...
Wesley T. O’Neal, Harish Gudi, Mahesh Chandrasekhar, Christopher Schumann, Autumn Birch, Sarah Mullen, Nicholas Ng, Michael Morris   +7 more
doaj   +1 more source

On Properties of Semipositive Cones and Simplicial Cones

The Electronic Journal of Linear Algebra, 2020
For a given nonsingular $n\times n$ matrix $A$, the cone $S_{A}=\{x:Ax\geq 0\}$ , and its subcone $K_A$ lying on the positive orthant, called as semipositive cone, are considered. If the interior of the semipositive cone $K_A$ is not empty, then $A$ is named as semipositive matrix. It is known that $K_A$ is a proper polyhedral cone.
Aritra Narayan Hisabia, Manideepa Saha
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Endoscopic Repair of the Distal Biceps Tendon

Arthroscopy Techniques
Distal biceps ruptures are common orthopaedic injuries that may result in cosmetic deformity, loss of subjective flexion strength, and loss of objective supination strength if treated nonoperatively.
Steven Bokshan, M.D.
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Interview with Chris Cone, Portland Fashion Week, 2011 (audio) [PDF]

, 2011
Interview of Chris Cone by Daniel Grey on February 22nd, 2011.
Cone, Chris
core   +1 more source

A New Topological Approach to Target the Existence of Solutions for Nonlinear Fractional Impulsive Wave Equations

Axioms, 2022
This paper considers a class of fractional impulsive wave equations and improves a previous results. In fact, this paper adopts a new topological approach to prove the existence of classical solutions with a complex arguments caused by impulsive ...
Svetlin G. Georgiev, Keltoum Bouhali, Khaled Zennir   +2 more
doaj   +1 more source