Results 31 to 40 of about 380,078 (313)

Theoretical and experimental studies of a novel cone-jet sensor

open access: yes, 2001
Modeling of a novel cone-jet sensor using two-dimensional (2-D) finite element analysis was investigated for dimensional measurement. Theoretical and experimental studies demonstrated that a cone-jet sensor supplied with air can be used to accurately ...
Jones, BE, Butler, C, Xie, T, Yang, QP
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

On Properties of Semipositive Cones and Simplicial Cones

open access: yesThe Electronic Journal of Linear Algebra, 2020
For a given nonsingular $n\times n$ matrix $A$, the cone $S_{A}=\{x:Ax\geq 0\}$ , and its subcone $K_A$ lying on the positive orthant, called as semipositive cone, are considered. If the interior of the semipositive cone $K_A$ is not empty, then $A$ is named as semipositive matrix. It is known that $K_A$ is a proper polyhedral cone.
Aritra Narayan Hisabia, Manideepa Saha
openaire   +3 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Locality and causality properties of light cone string field theory [PDF]

open access: yes, 2004
The recent discovery of a new maximally supersymmetric background for the type IIB superstring theory has revived the interest in light cone string field theory.
Kyritisis, Konstantinos
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Antibiotic Stewardship at transitions of care: identifying opportunities for antibiotic optimization

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
We conducted a cross-sectional study to identify the frequency of optimized oral antibiotic regimens at transitions of care (TOC) in patients diagnosed with respiratory, urinary tract, or skin structure infections. An optimal regimen was identified in 62.
Corey Johnson   +3 more
doaj   +1 more source

A New Topological Approach to Target the Existence of Solutions for Nonlinear Fractional Impulsive Wave Equations

open access: yesAxioms, 2022
This paper considers a class of fractional impulsive wave equations and improves a previous results. In fact, this paper adopts a new topological approach to prove the existence of classical solutions with a complex arguments caused by impulsive ...
Svetlin G. Georgiev   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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