Results 241 to 250 of about 15,516 (285)

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

open access: yesAdvanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu   +10 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Focusing on color: How the eye chooses which wavelength to see best. [PDF]

open access: yesSci Adv
Chin BM   +4 more
europepmc   +1 more source

Enhancing CBCT-based CT synthesis using planning MRI in adaptive proton therapy for head cancer: A deep learning approach. [PDF]

open access: yesJ Appl Clin Med Phys
Molina-Maza JM   +9 more
europepmc   +1 more source

A heterogeneous population code at the first synapse of vision. [PDF]

open access: yesNat Commun
Herzog T   +5 more
europepmc   +1 more source

Error-Tolerant Multimodal Vision-Language Models for Endodontic Triaging: A Cross-Sectional Study. [PDF]

open access: yesInt J Dent
Titu MFS   +7 more
europepmc   +1 more source

Applications of cut polyhedra - I.

open access: yes
Deza, M.M., Laurent, M.
core  

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