Results 51 to 60 of about 68,007 (274)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Empirical geodesic graphs and CAT(k) metrics for data analysis

open access: yes, 2019
A methodology is developed for data analysis based on empirically constructed geodesic metric spaces. For a probability distribution, the length along a path between two points can be defined as the amount of probability mass accumulated along the path ...
Kobayashi, Kei, Wynn, Henry P.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Unique geodesics for Thompson's metric [PDF]

open access: yes, 2013
In this paper a geometric characterization of the unique geodesics in Thompson's metric spaces is presented. This characterization is used to prove a variety of other geometric results.
Lemmens, Bas, Roelands, Mark
core  

Invariant approximation results in‎ ‎cone metric spaces

open access: yesAnnals of Functional Analysis, 2011
Some sufficient conditions for the existence of fixed point of mappings satisfying generalized weak contractive conditions is obtained. A fixed point theorem for nonexpansive mappings is also obtained. As an application, some invariant approximation results are derived in cone metric spaces.
Abbas, M, VETRO, Pasquale
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Coupled Coincidence Points in Partially Ordered Cone Metric Spaces with a c-Distance

open access: yesJournal of Applied Mathematics, 2012
Cho et al. (2012) proved some coupled fixed point theorems in partially ordered cone metric spaces by using the concept of a c-distance in cone metric spaces. In this paper, we prove some coincidence point theorems in partially ordered cone metric spaces
Wasfi Shatanawi   +2 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Completion Of Cone Metric Spaces

open access: yes, 2009
In this paper a completion theorem for cone metric spaces and a completion theorem for cone normed spaces are proved. The completion spaces are defined by means of an equivalence relation obtained by convergence via the scalar norm of the Banach space E.
Çakallı, Hüseyin, Sönmez, Ayşe
openaire   +5 more sources

Quasicone Metric Spaces and Generalizations of Caristi Kirk's Theorem

open access: yesFixed Point Theory and Applications, 2009
Cone-valued lower semicontinuous maps are used to generalize Cristi-Kirik's fixed point theorem to Cone metric spaces. The cone under consideration is assumed to be strongly minihedral and normal.
Karapinar Erdal, Abdeljawad Thabet
doaj  

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