This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
Correlation of Bond Strength and Dentinal Tubule Penetration Evaluation of Four Different Endodontic Sealers: AH Plus, MTA Fillapex, Endoseal MTA, and Endoseal TCS (Maruchi): An In Vitro Study. [PDF]
Mirzaei Sadeghloo A +3 more
europepmc +1 more source
A Covalent 3D CNT@rGO Nano‐Hybrid for High‐Efficiency Conductivity in Lithium‐Ion Batteries
A facile one‐step CVD strategy achieves high‐yield (7692.31%) growth of CNTs on rGO, forming a covalently bonded 3D CNT@rGO hybrid. This structure enables multidirectional conductive networks in LiFePO4 cathodes, delivering superior rate performance, high ICE (99.88%), and 96.32% capacity retention after 300 cycles at 1 C.
Junwen Tang +10 more
wiley +1 more source
Root Canal Obturation Quality in 3D-Printed C-Shaped Canals with Different Filling Techniques. [PDF]
Fu D +6 more
europepmc +1 more source
A method for estimating coefficient of lateral earth pressure based on cone penetration tests
Donggun Nam, Qaisar Abbas, Junhwan Lee
openalex +1 more source
Determination of undrained strengths by cone penetration tests.
Calculations have been presented for the loads on a cone penetrometer in a cohesive material, with the validity of the calculations being limited at present to a penetrometer near the surface of a soil. The undrained strength of a cohesive soil could therefore be back-analysed from measurements of loads on cone penetrometers.
Houlsby, G, Wroth, C
openaire +2 more sources
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
Enhancing the Ultrasonic Welding of Wood Using 3D Printed Lignin Energy Directors
Sustainable manufacturing for lightweight structures using ecofriendly materials will be key to reducing material consumption and lowering carbon footprints. Here, an approach is presented to weld wood using ultrasonic vibrations with material at the joint interface to direct energy.
Muhamad Amani +6 more
wiley +1 more source
Evaluation of the impact of blast damage on tunnel surrounding rock induced by C-type cumulative tube cone angle. [PDF]
Guo J, Fei H, Ji H, Bao S, Hu G, Yan Y.
europepmc +1 more source

