Results 221 to 230 of about 88,835 (298)

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

open access: yesAdvanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen   +6 more
wiley   +1 more source

A Shear Thickening Colloidal Suspension Functioning via Progressive Impact Jamming with Persistent Lubrication Layer

open access: yesAdvanced Science, EarlyView.
An ionic liquid‐based shear‐thickening fluid (ILSTF) exhibits lubricated dynamics from strong shear thickening to impact‐triggered jamming. A persistent nanometric solvation layer around silica governs both the shear thickening saturation in rheology and jamming front propagation under dynamic impact compression.
Yiran Wu   +6 more
wiley   +1 more source

High‐Resolution Multispectral Photovoltaic Imagers from Visible to Short‐Wave Infrared

open access: yesAdvanced Science, EarlyView.
We demonstrate a monolithic quad‐spectral imager that seamlessly integrates visible and short‐wave infrared detection on a single chip. Through direct photopatterning of an all‐polymer bulk heterojunction and colloidal quantum dots, the device achieves high‐resolution (640 × 512) imaging across 350–2400 nm, enabling multispectral capture for ...
Wanqing Li   +12 more
wiley   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

open access: yesAdvanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin   +12 more
wiley   +1 more source

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