Results 21 to 30 of about 8,968 (265)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Materials of the Third Conference “The Constitution of Russia Yesterday, Today, Tomorrow” (St. Petersburg, December 9–10, 2019), second part

Теоретическая и прикладная юриспруденция, 2020
This material is devoted to a review of expert speeches at the Conference “The Constitution of Russia: Yesterday, Today, Tomorrow”, held in St. Petersburg on December 9–10, 2019. The problems of modern federalism were discussed at the conference.
article editotial
doaj  

Inkade ja asteekide riikliku ning ühiskondliku korralduse võrdlusjooni [PDF]

Mäetagused, 2006
During the period under consideration (1438-1532) the Inca state in Peru was politically a highly centralised empire with a strong central government.
Tarmo Kulmar
doaj  

The development of a global Midwifery Education Accreditation Programme

Global Health Action, 2018
Background: Many countries are responding to the global shortage of midwives by increasing the student intake to their midwifery schools. At the same time, attention must be paid to the quality of education being provided, so that quality of midwifery ...
Andrea Nove, Sally Pairman, Leah F. Bohle, Shantanu Garg, Nester T. Moyo, Michaela Michel-Schuldt, Axel Hoffmann, Gonçalo Castro   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Modificaciones constitucionales en Bélgica. La "sixième réforme" de l'Etat: Un proceso en marcha [PDF]

Revista d'Estudis Autonòmics i Federals, 2015
The Accord du Papillon started the Belgium Sexième réforme de l’Etat. After a long institutional crisis, an agreement between the major parties seemed the best way to ensure a stable government to the country and to enhance a new season of constitutional
Anna Mastromarino
doaj  

Drafting of the Union treaty in September-December 1991: from the dismantling of statehood to the USSR's collapse

Управление, 2018
The article is devoted to the consideration of internal political processes in the Soviet Union at the final stage of its existence, in particular, the political struggle between the President of the USSR M.S.
A. V. Lukashin
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Historia, vida y contradicciones en las Trece Colonias

Alejandría, 2023
In this brief article I expose the historical conditions prior to the colonization of North America, the colonization itself together with its previous historical context and the social conditions of these settlers.
José Antonio Martínez Amador
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