Results 41 to 50 of about 9,644,665 (267)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Abstracts of reports from the 55th annual Western Orchard Pest and Disease Management Conference
Proceedings of the 55th Annual Western Orchard Pest and Disease Management Conference, held January 20-22, 1981 at the Imperial Hotel in Portland, Oregon.These abstracts of progress reports on research conducted on the principal insect and disease pests ...
Western Orchard Pest and Disease Management Conference
core +6 more sources
ISME Commission on Music in Special Education, Music Therapy and Music Medicine (12-14 July 2012, Greece) [PDF]
The ISME Commission on Music in Special Education, Music Therapy and Music Medicine was held on 12-14 July 2012, as part of the pre-conference commission seminars of the 30th ISME World Conference “Music Paedeia: From Ancient Greek ...
Abstracts, Conference
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ISME Commission on Music in Special Education, Music Therapy and Music Medicine (17-18 July 2014, Brazil) [PDF]
The ISME Commission on Music in Special Education, Music Therapy and Music Medicine was held on 17-18 July 2014, as part of the pre-conference commission seminars of the 31st ISME World Conference “Listening to the Musical Diversity of the ...
Abstracts, Conference
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Program and abstracts from the 2008 Neurospora conference [PDF]
Program and abstracts from the 2008 Neurospora Conference, March 27-30, Pacific Grove ...
Neurospora Conference
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

