Results 131 to 140 of about 1,958,177 (316)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Stratigraphy and development of the Late Miocene-Early Pleistocene Hawke’s Bay forearc basin [PDF]
A Late Miocene-Early Pleistocene mixed carbonate-siliciclastic sedimentary succession about 2 500 m thick in the Hawke’s Bay forearc basin is the focus of a basin analysis. The area under investigation covers 3 500 km2 of western and central Hawke’s Bay.
Bland, Kyle J. +2 more
core +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
A Metadata-Enabled Scientific Discourse Platform [PDF]
Scientific papers and scientific conferences are still, despite the emergence of several new dissemination technologies, the de-facto standard in which scientific knowledge is consumed and discussed.
Chenu-Abente, Ronald +3 more
core
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Major Conference Bias and the NCAA Men's Basketball Tournament [PDF]
The following paper examines the potential bias by the NCAA men's basketball selection committee in favor of major conferences. Employing data from the 1997 – 2006 tournaments, we find evidence for bias in the tournament seeding of teams from the six ...
Timothy Zimmer, Todd Kuethe
core
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
“…i [sic] only renew [my ALA membership] out of a sense of professional obligation, and also because of the fear that i’ll [sic] put it on my resume and get busted as not being a member.” –c-dog Membership in the American Library Association ...
Emily Ford
doaj

