Results 91 to 100 of about 3,336,575 (289)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Distributed Simultaneous Inference in Generalized Linear Models via Confidence Distribution. [PDF]
J Multivar Anal, 2020 Tang L, Zhou L, Song PX.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
PARAMETER ESTIMATION AND CONFIDENCE LIMIT CALCULATION METHOD OF THREE-PARAMETER WEIBULL DISTRIBUTION
Jixie qiangduA correlation-regression method was proposed to solve the problem of low accuracy of parameter estimation and confidence limit calculation of the three-parameter Weibull distribution.The method was combined by the correlation coefficient method(Fu method)
ZHANG JianFeng +4 more
doaj
Stochastic Assessment of Voltage Sags in Distribution Networks
Iranian Journal of Electrical and Electronic Engineering, 2008 This paper compares fault position and Monte Carlo methods as the most common methods in stochastic assessment of voltage sags. To compare their abilities, symmetrical and unsymmetrical faults with different probability distribution of fault positions ...
M. Aliakbar-Golkar, Y. Raisee-Gahrooyi
doaj
"Set Inference in Latent Variables Models" [PDF]
We propose a methodology for constructing valid confidence regions in incomplete models with latent variables satisfying moment equality restrictions. These include moment equality and inequality models with latent variables.
Isabel Mourifie, Marc Henry
core
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source