Results 121 to 130 of about 3,060,296 (340)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

Stochastic Assessment of Voltage Sags in Distribution Networks

open access: yesIranian Journal of Electrical and Electronic Engineering, 2008
This paper compares fault position and Monte Carlo methods as the most common methods in stochastic assessment of voltage sags. To compare their abilities, symmetrical and unsymmetrical faults with different probability distribution of fault positions ...
M. Aliakbar-Golkar, Y. Raisee-Gahrooyi
doaj  

A Distribution-Free Confidence Interval for the Mean

open access: yesThe Annals of Mathematical Statistics, 1948
Consider a random sample of $N$ observations $x_1, x_2, \cdots, x_N,$ from a universe of mean $\mu$ and variance $\sigma^2$. Let $m$ and $s^2$ be the sample mean and variance respectively: \begin{equation*}\tag{1} m = \frac{1}{N} \sum^N_{i=1} x_i,\quad s^2 = \frac{1}{N} \sum^N_{i=1} (x_i - m)^2.\end{equation*} It is shown that the following ...
openaire   +3 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin   +5 more
wiley   +1 more source

PARAMETER ESTIMATION AND CONFIDENCE LIMIT CALCULATION METHOD OF THREE-PARAMETER WEIBULL DISTRIBUTION

open access: yesJixie qiangdu
A correlation-regression method was proposed to solve the problem of low accuracy of parameter estimation and confidence limit calculation of the three-parameter Weibull distribution.The method was combined by the correlation coefficient method(Fu method)
ZHANG JianFeng   +4 more
doaj  

Advantages and limitations of navigation‐based multicriteria optimization (MCO) in selectively sparing pharyngeal constrictor muscles in head and neck radiotherapy treatment planning

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Sparing pharyngeal constrictor muscles (PCMs) during radiotherapy improves patient‐reported swallowing function. This study aimed to explore the feasibility of integrating knowledge‐based planning (KBP) with multicriteria optimization (MCO) in Eclipse v18.0 to selectively spare PCM, quantify the required trade‐off in prophylactic ...
Laura K. Howard   +3 more
wiley   +1 more source

PARAMETER ESTIMATION AND CONFIDENCE LIMIT CALCUALTION METHOD OF THREE-PARAMETER WEIBULL DISTRIBUTION

open access: yesJixie qiangdu
A correlation-regression method was proposed to solve the problem of low accuracy of parameter estimation and confidence limit calculation of the three-parameter Weibull distribution.The method was combined by the correlation coefficient method (Fu ...
ZHANG JianFeng   +4 more
doaj  

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