Results 51 to 60 of about 3,336,575 (289)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Technique for confidence interval calculating for estimating of the random value subordinated to the composition of normal and uniform distributions

Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2019
The general case of determining of probability of hit by a given section of a random variable subordinated to the composition of normal and uniform distribution laws having arbitrary distribution centers is considered. A technique for confidence interval
E. L. Kreidik
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Edgeworth and Cornish Fisher expansions and confidence intervals for the distribution, density and

Statistica, 2013
We show that kernel density estimates of bandwidth h=h(n)→0 satisfy the Cornish-Fisher assumption with parameter m=nh. This allows Cornish-Fisher expansions about the normal for standardized and Studentized kernel density estimates.
Christopher S. Withers, Saralees Nadarajah   +1 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Bootstrap confidence intervals for the process capability index under half-logistic distribution [PDF]

Maejo International Journal of Science and Technology, 2012
This study concerns the construction of bootstrap confidence intervals for theprocess capability index in the case of half-logistic distribution. The bootstrap confidence intervals applied consist of standard bootstrap confidence interval, percentile ...
Wararit Panichkitkosolkul
doaj  

Micro-organism distribution sampling for bioassays [PDF]

, 1975
Purpose of sampling distribution is to characterize sample-to-sample variation so statistical tests may be applied, to estimate error due to sampling (confidence limits) and to evaluate observed differences between samples. Distribution could be used for
Nelson, B. A.
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

INTERVALOS DE CONFIANZA PARA LA COMPARACIÓN DE DOS PROPORCIONES INTERVALOS DE CONFIANZA PARA LA COMPARACIÓN DE DOS PROPORCIONES

Revista Colombiana de Estadística, 2003
La construcción de intervalos de confianza para la estimación de pi_1 − pi_2, la diferencia entre dos proporciones, es un problema importante en el trabajo estadístico aplicado. Revisamos diferentes procedimientos de construcción y mediante un estudio de
Correa Juan Carlos, Sierra Esperanza
doaj