Results 71 to 80 of about 3,223,931 (336)

Genus Topology of the Cosmic Microwave Background from the WMAP 3-Year Data

open access: yes, 2006
We have independently measured the genus topology of the temperature fluctuations in the cosmic microwave background seen in the Wilkinson Microwave Anisotropy Probe (WMAP) 3-year data.
C. Mugnolo   +6 more
core   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Using confidence distribution sampling to visualize confidence sets

open access: yesStatistica Sinica, 2011
This paper presents a new sampling-based methodology designed to fa- cilitate the visual analysis of the confidence sets generated by an inference function such as the likelihood. This methodology generates a sample of parameters from a confidence distribution.
Kim, Daeyoung, Lindsay, Bruce G
openaire   +3 more sources

Confidence Distribution and Distribution Estimation for Modern Statistical Inference

open access: yes, 2023
To appear as a chapter in Springer Handbook of Engineering Statistics, 2nd ...
Yifan Cui, Min-ge Xie
openaire   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

INTERVALOS DE CONFIANZA PARA LA COMPARACIÓN DE DOS PROPORCIONES INTERVALOS DE CONFIANZA PARA LA COMPARACIÓN DE DOS PROPORCIONES

open access: yesRevista Colombiana de Estadística, 2003
La construcción de intervalos de confianza para la estimación de pi_1 − pi_2, la diferencia entre dos proporciones, es un problema importante en el trabajo estadístico aplicado. Revisamos diferentes procedimientos de construcción y mediante un estudio de
Correa Juan Carlos, Sierra Esperanza
doaj  

Bootstrap confidence intervals for the process capability index under half-logistic distribution [PDF]

open access: yesMaejo International Journal of Science and Technology, 2012
This study concerns the construction of bootstrap confidence intervals for theprocess capability index in the case of half-logistic distribution. The bootstrap confidence intervals applied consist of standard bootstrap confidence interval, percentile ...
Wararit Panichkitkosolkul
doaj  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Integrating Surface-related Indicators of Coverage, Distance and Distribution for Quantifying Scan-to-BIM Confidence Level [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Scan-to-BIM is a widely-used approach to generate Building Information Modelling and by extension Digital Twin models in the architecture, engineering, and construction sector.
S. Malihi, F. Bosché
doaj   +1 more source

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