Results 81 to 90 of about 3,336,575 (289)

Confidence Intervals for Function of Percentiles of Birnbaum-Saunders Distributions Containing Zero Values with Application to Wind Speed Modelling

open access: yesModelling
The Birnbaum–Saunders (BS) distribution, defined only for non-negative values, is asymmetrical. However, it can be transformed into a normal distribution, which is symmetric.
Warisa Thangjai   +3 more
doaj   +1 more source

Accurate Jitter Computation in CNA Breakpoints Using Hybrid Confidence Masks With Applications to SNP Array Probing

open access: yesIEEE Access, 2018
Chromosomal structural changes known as copy number alterations-aberrations (CNAs) result in gains or losses in copies of deoxyribonucleic acid sections, which are typically associated with different types of cancer. An intensive noise inherent to modern
Jorge Munoz-Minjares   +4 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Managing the Risk via the Chi-Squared Distribution in VaR and CVaR with the Use in Generalized Autoregressive Conditional Heteroskedasticity Model

open access: yesMathematics
This paper develops a framework for quantifying risk by integrating analytical derivations of Value at Risk (VaR) and Conditional VaR (CVaR) under the chi-squared distribution with empirical modeling via Generalized Autoregressive Conditional ...
Fazlollah Soleymani, Qiang Ma, Tao Liu
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Uncertainty and Disagreement in Forecasting Inflation: Evidence from the Laboratory (Replaced by CentER DP 2012-072) [PDF]

open access: yes
We establish several stylized facts about the behavior of individual uncertainty and disagreement between individuals when forecasting inflation in the laboratory.
Pfajfar, D., Zakelj, B.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

INTEGRATED BAYESIAN CONFIDENCE RELIABILITY EVALUATION MODEL BASED ON WEIBULL TYPE ZERO-FAILURE DATA

open access: yesJixie qiangdu, 2020
In the case of no-fault data,the failure probability combined with the Bayesian theory to study the confidence limit analysis to correct the unilateral confidence reliability evaluation. Based on the Weibull distribution,the distribution curve method was
HE WuHui, TANG JiaYin
doaj  

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