Results 81 to 90 of about 3,223,931 (336)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Monte Carlo Comparison of Approximate Tolerance Intervals for the Poisson Distribution

open access: yesپژوهش‌های ریاضی, 2016
The problem of finding  tolerance intervals receives very much attention of researchers and are widely used in various statistical fields, including biometry, economics, reliability analysis and quality control.
M Naghizadeh ghomi, A Noroozi Firoze
doaj  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Jackknife Empirical Likelihood-based inference for S-Gini indices

open access: yes, 2018
Widely used income inequality measure, Gini index is extended to form a family of income inequality measures known as Single-Series Gini (S-Gini) indices.
Kattumannil, Sudheesh K   +2 more
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Selecting the number of principal components: estimation of the true rank of a noisy matrix [PDF]

open access: yes, 2015
Principal component analysis (PCA) is a well-known tool in multivariate statistics. One significant challenge in using PCA is the choice of the number of components.
Choi, Yunjin   +2 more
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Confidence relative off-targets distance-based multi-dimensional transparency evaluation of distribution station area

open access: yesFrontiers in Energy Research
With the large-scale integration of distributed renewable energy into low-voltage distribution station areas, rapidly growing services put forward new requirements on transparent monitoring.
Jie Ren   +8 more
doaj   +1 more source

Cultural Repercussions: Extending Our Knowledge about How Values of Trust and Confidence Influence Tax Structures within Europe [PDF]

open access: yesInternational Journal of Management, Knowledge and Learning, 2012
Within a unified Europe that is heading towards ever more harmonization,it is interesting to examine why there exists such diversity in tax regimesamong its countries.
Hanna Lierse, Rune Ellemose Gulev
doaj  

A Distribution-Free Confidence Interval for the Mean

open access: yesThe Annals of Mathematical Statistics, 1948
Consider a random sample of $N$ observations $x_1, x_2, \cdots, x_N,$ from a universe of mean $\mu$ and variance $\sigma^2$. Let $m$ and $s^2$ be the sample mean and variance respectively: \begin{equation*}\tag{1} m = \frac{1}{N} \sum^N_{i=1} x_i,\quad s^2 = \frac{1}{N} \sum^N_{i=1} (x_i - m)^2.\end{equation*} It is shown that the following ...
openaire   +3 more sources

Home - About - Disclaimer - Privacy