Results 31 to 40 of about 1,630,281 (234)
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]
, 2016 Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H. +6 more
core +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Markov Chain Monte Carlo confidence intervals
, 2016 For a reversible and ergodic Markov chain $\{X_n,n\geq0\}$ with invariant distribution $\pi$, we show that a valid confidence interval for $\pi(h)$ can be constructed whenever the asymptotic variance $\sigma^2_P(h)$ is finite and positive.
Atchadé, Yves F.
core +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
An SPSS Macro to Compute Confidence Intervals for Pearsons Correlation [PDF]
Tutorials in Quantitative Methods for Psychology, 2014 In many disciplines, including psychology, medical research, epidemiology and public health, authors are required, or at least encouraged to report confidence intervals (CIs) along with effect size estimates.
Bruce Weaver, Ray Koopman
doaj
Correlation Coefficients: Mean Bias and Confidence Interval Distortions
Journal of Methods and Measurement in the Social Sciences, 2011 Non-zero correlation coefficients have non-normal distributions, affecting both means and standard deviations. Previous research suggests that z transformation may effectively correct mean bias for N's less than 30. In this study, simulations with small (
Richard L. Gorsuch, Curtis S. Lehmann
doaj +1 more source
Alternatives to P value: confidence interval and effect size [PDF]
Korean Journal of Anesthesiology, 2016 The previous articles of the Statistical Round in the Korean Journal of Anesthesiology posed a strong enquiry on the issue of null hypothesis significance testing (NHST).
Dong Kyu Lee
doaj +1 more source
Ceramide remodeling and risk of cardiovascular events and mortality [PDF]
, 2018 BackgroundRecent studies suggest that circulating concentrations of specific ceramide species may be associated with coronary risk and mortality. We sought to determine the relations between the most abundant plasma ceramide species of differing acyl ...
Dorr, Marcus +14 more
core +2 more sources
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source