Results 41 to 50 of about 2,097,293 (339)
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
A Method for Confidence Intervals of High Quantiles
Entropy, 2021 The high quantile estimation of heavy tailed distributions has many important applications. There are theoretical difficulties in studying heavy tailed distributions since they often have infinite moments.
Mei Ling Huang, Xiang Raney-Yan
doaj +1 more source
Becoming confident about confidence intervals [PDF]
The Bone & Joint Journal, 2017 A clear understanding of variability is at the heart of many of the studies published in The Bone & Joint Journal . The terms variability, dispersion, spread, distribution and variance, amongst others, are used to refer to the range of values within a dataset.
Perry, DC +5 more
openaire +3 more sources
Better Binomial Confidence Intervals [PDF]
, 2007 The construction of a confidence interval for a binomial parameter is a basic analysis in statistical inference. Most introductory statistics textbook authors present the binomial confidence interval based on the asymptotic normality of the sample ...
Reed, James F., III
core +2 more sources
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Image Segmentation Based on Statistical Confidence Intervals
Entropy, 2018 Image segmentation is defined as a partition realized to an image into homogeneous regions to modify it into something that is more meaningful and softer to examine.
Pablo Buenestado, Leonardo Acho
doaj +1 more source
Predictive physiological anticipatory activity preceding seemingly unpredictable stimuli: An update of Mossbridge et al\u2019s meta-analysis [PDF]
, 2018 Background: This is an update of the Mossbridge et al\u2019s meta-analysis related to the physiological anticipation preceding seemingly unpredictable stimuli which overall effect size was 0.21; 95% Confidence Intervals: 0.13 - 0.29 Methods: Nineteen new
Duggan, Michael, Tressoldi, Patrizio
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Improved Confidence Intervals for Expectiles
MathematicsExpectiles were introduced to statistics around 40 years ago, but have recently gained renewed interest due to their relevance in financial risk management.
Spiridon Penev, Yoshihiko Maesono
doaj +1 more source
Better Confidence Intervals for a Binomial Proportion
Communications, 2010 Interval estimation of a binomial proportion is one of the basic problems in statistics. In technical practice a binomial proportion is often used in statistical quality control.
Ivana Pobocikova
doaj +1 more source