Results 41 to 50 of about 962,551 (312)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Democratic Confidence Intervals for comparing two Proportions [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2013
We offer methods to create an accurate graph for comparing confidence intervals for two proportions. The firstmethod involves using weighted sum contrasts when fitting logistic regression with a binary explanatory variable.
Phattrawan Tongkumchum   +3 more
doaj  

Confidence intervals: Concepts, fallacies, criticisms, solutions and beyond [PDF]

open access: yesNetwork Biology, 2022
For a long time, confidence interval theory is the basis of statistics, and confidence interval has been regarded as an important content of statistical analysis.
WenJun Zhang
doaj  

Inferential Statistics Is an Unfit Tool for Interpreting Data

open access: yesApplied Sciences, 2022
Null hypothesis significance testing is a commonly used tool for making statistical inferences in empirical studies, but its use has always been controversial. In this manuscript, I argue that even more problematic is that significance testing, and other
Anders Sand
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

p value and confidence intervals

open access: yesCurrent Medicine Research and Practice, 2012
In any research after obtaining the results, the researcher wants to know whether the results obtained are statistically significant or not. The statistical significance is usually expressed as p value or confidence intervals.
Vivek Choudhury   +2 more
doaj  

Inference for the Weibull Distribution: A tutorial [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2015
This tutorial deals with the 2-parameter Weibull distribution. In particular it covers the construction of confidence bounds and intervals for various parameters of interest, the Weibull scale and shape parameters, its quantiles and tail probabilities ...
Scholz, F. W.
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Effect size, confidence intervals and statistical power in psychological research. [PDF]

open access: yesPsychology in Russia: State of Art, 2015
Quantitative psychological research is focused on detecting the occurrence of certain population phenomena by analyzing data from a sample, and statistics is a particularly helpful mathematical tool that is used by researchers to evaluate hypotheses and ...
Téllez A.   +2 more
doaj   +1 more source

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