Results 51 to 60 of about 3,328,774 (379)

A Method for Confidence Intervals of High Quantiles

open access: yesEntropy, 2021
The high quantile estimation of heavy tailed distributions has many important applications. There are theoretical difficulties in studying heavy tailed distributions since they often have infinite moments.
Mei Ling Huang, Xiang Raney-Yan
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Temporal Exponential Random Graph Models with btergm: Estimation and Bootstrap Confidence Intervals

open access: yes, 2018
The xergm package is an implementation of extensions to the exponential random graph model (ERGM). It acts as a meta-package for multiple constituent packages.
Philip Leifeld   +2 more
semanticscholar   +1 more source

Measuring inter-rater reliability for nominal data – which coefficients and confidence intervals are appropriate?

open access: yesBMC Medical Research Methodology, 2016
BackgroundReliability of measurements is a prerequisite of medical research. For nominal data, Fleiss’ kappa (in the following labelled as Fleiss’ K) and Krippendorff’s alpha provide the highest flexibility of the available reliability measures with ...
A. Zapf   +3 more
semanticscholar   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Image Segmentation Based on Statistical Confidence Intervals

open access: yesEntropy, 2018
Image segmentation is defined as a partition realized to an image into homogeneous regions to modify it into something that is more meaningful and softer to examine.
Pablo Buenestado, Leonardo Acho
doaj   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Better Confidence Intervals for a Binomial Proportion

open access: yesCommunications, 2010
Interval estimation of a binomial proportion is one of the basic problems in statistics. In technical practice a binomial proportion is often used in statistical quality control.
Ivana Pobocikova
doaj   +1 more source

Fletcher-Turek Model Averaged Profile Likelihood Confidence Intervals [PDF]

open access: yesModel-averaged confidence intervals. Scandinavian Journal of Statistics, 43, 35-48 (2016), 2014
We evaluate the model averaged profile likelihood confidence intervals proposed by Fletcher and Turek (2011) in a simple situation in which there are two linear regression models over which we average. We obtain exact expressions for the coverage and the scaled expected length of the intervals and use these to compute these quantities in particular ...
arxiv   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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