Results 101 to 110 of about 3,488,035 (299)
THE CONFIGURATION OF STENDOMYCIDINE
The Journal of Antibiotics, 1970 The absolute configuration of stendomycidine (I), a constituent of the peptide antibiotic stendomycin, was determined. Optical rotatory dispersion (ORD) measurements showed the configuration at the α-carbon atom to be that of an L-amino acid. Degradation of stendomycidine with N-bromosuccinimide yielded 2-methylimino-3-methyl-hexahydropyrimidine-4 ...
G G, Marconi, M, Bodanszky
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FlowWe present the design, construction and initial experimental validation of the Northwestern Polytechnical University Taylor–Couette (NPU-TC) apparatus, specifically developed to explore turbulent Taylor–Couette flows under conditions relevant to ultra ...
Xi-Ran Liu +4 more
doaj +1 more source
Avian Conservation and Ecology, 2007 Conservation of biodiversity is now a firmly entrenched objective of sustainable forest management, and emulating natural disturbance has been widely adopted as a conservation strategy. Yet the foundation for this approach is still very much a hypothesis
Robert S. Rempel
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A novel trajectories optimizing method for dynamic soaring based on deep reinforcement learning
Defence TechnologyDynamic soaring, inspired by the wind-riding flight of birds such as albatrosses, is a biomimetic technique which leverages wind fields to enhance the endurance of unmanned aerial vehicles (UAVs).
Wanyong Zou +4 more
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Risk Management and Healthcare Policy, 2021 Zhiguang Li,1 Wanying Zhang,1 Aijie Kong,1 Zhiyuan Ding,1 Hua Wei,1 Yige Guo2 1School of Economics and Management, Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2King’s Business School, King’s College ...
Li Z +5 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Measurement Model and Precision Analysis of Accelerometers for Maglev Vibration Isolation Platforms
Sensors, 2015 High precision measurement of acceleration levels is required to allow active control for vibration isolation platforms. It is necessary to propose an accelerometer configuration measurement model that yields such a high measuring precision.
Qianqian Wu +6 more
doaj +1 more source