Results 161 to 170 of about 72,565 (315)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Bibliografie / Il confine orientale italiano
, 2015 Il confine orientale italiano è stato oggetto di perduranti e sanguinosi conflitti politici e militari a causa del crocevia identitario, culturale e nazionalistico che questo confine ha attraversato in tutti i suoi spostamenti, dalla crisi dell'Impero ...
Elena Franchini
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Le frontiere, nate per essere una barriera tra Stati, si possono trasformare in ponti che spingono gli abitanti delle aree circostanti ad attraversare la barriera per trarne vantaggi in situazioni di libera circolazione.
Ferrara, Maria Dolores
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Le posthumain confiné : la membrane synhaptique
Revue des Sciences Humaines, 2021 Pierre Cassou-Noguès
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Segmental strain in chronic ischemic cardiomyopathy: clarifying the role of multiple-comparison adjustment and the clinical interpretation of limits of agreement. [PDF]
J Cardiovasc ImagingMalik MMUD, Jayaswal RP.
europepmc +1 more source