Results 261 to 270 of about 72,565 (315)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Su alcune rettifiche del confine italo-svizzero

Bollettino della Società Geografica Italiana, 1956
Antonio Norcen
doaj  

On-chip microwave oscillator in deep-subwavelength scale based on spoof plasmonic skyrmions. [PDF]

Natl Sci Rev
Wang WZ, Liu Y, Zhang X, Gao ZL, Tang XS, Cui TJ.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Low-Dimensional Materials for Future Transistors. [PDF]

Nanomicro Lett
Zhang S, Hong Z, Ren M, Zhu L, Wang J.
europepmc   +1 more source

Cavity Effect of Gold Nanoparticles on Mid-Infrared Light. [PDF]

ACS Omega
Yu W, Yang C, Min H, Liu H, Ma Y, Yu Z, Yuan S, Dong H, Wang K, Song B, Feng J.   +10 more
europepmc   +1 more source

Growing Sodiophilic ZnO Nanorod Arrays on Al Substrate for High-Energy-Density Anode-Free Na Batteries. [PDF]

J Am Chem Soc
An Y, Pei Z, Luan D, Lou XWD.
europepmc   +1 more source

Photoelectrochemical Immuno-Sensing via Plasmon-Induced Resonance Energy Transfer Mechanism. [PDF]

ECS Sens Plus
Bright J, Hang Y, Tan W, Wang A, Yang H, Wu N.   +5 more
europepmc   +1 more source