Results 111 to 120 of about 428,494 (345)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pneumatic tourniquet work safety scale: A confirmatory factor analysis

open access: yesJournal of Perioperative Nursing
Objective: Although confirmatory factor analysis is an essential stage in validation of any instrument, the Pneumatic tourniquet work safety scale had not been subject to it.
Hamideh Fanoudi   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The application of multivariate statistical methods for understanding food consumer behaviour [PDF]

open access: yes
Understanding consumer behaviour is a necessary precondition for a targeted communication strategy. The behaviour is a complex phenomenon and research needs to undertake a rigorously apply sophisticated methods.
Banati, Diana   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Confirmatory factor analysis of the Athlete Satisfaction Questionnaire (ASQ) - Portuguese version / Análise confirmatória do Questionário de Satisfação do Atleta - versão Portuguesa

open access: yesPsicologia: Reflexão e Crítica, 2010
The purpose of this study was to examine the psychometric properties of the Portuguese version of the Athlete Satisfaction Questionnaire (ASQ), developed by Riemer and Chelladurai (1998), through confirmatory factor analysis since cultural and language ...
Carla M. Chicau Borrego   +4 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Confirmatory Factor Analysis

open access: yes, 2016
Let the positive correlations be observed among the test scores for physics, chemistry, and biology.
openaire   +2 more sources

Counterfeit self: A confirmatory factor analysis among Indonesians [PDF]

open access: yes
It is questionable whether counterfeiting in many areas of life contributes to unethical behavior to a wider extent. If the notion is supported by data, then the moral damage in a society could be prevented by reducing the counterfeit self and behavior ...
Abraham, Juneman   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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