Results 81 to 90 of about 158,010 (251)

Confirmatory Factor Analysis -- A Case study

CoRR, 2019
Confirmatory Factor Analysis (CFA) is a particular form of factor analysis, most commonly used in social research. In confirmatory factor analysis, the researcher first develops a hypothesis about what factors they believe are underlying the used measures and may impose constraints on the model based on these a priori hypotheses.
Rui Portocarrero Sarmento, Vera Costa
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Confirmatory factor analysis of the Athlete Satisfaction Questionnaire (ASQ) - Portuguese version / Análise confirmatória do Questionário de Satisfação do Atleta - versão Portuguesa

Psicologia: Reflexão e Crítica, 2010
The purpose of this study was to examine the psychometric properties of the Portuguese version of the Athlete Satisfaction Questionnaire (ASQ), developed by Riemer and Chelladurai (1998), through confirmatory factor analysis since cultural and language ...
Carla M. Chicau Borrego, José Carlos Leitão, José Alves, Carlos Silva, Joan Palmi   +4 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Psychometric properties of the Persian version of the Reinforcement Sensitivity Theory Personality Questionnaire (RST-PQ)

Acta Psychologica
Background: The Reinforcement Sensitivity Theory of Personality Questionnaire (RST-PQ) originated from the Revised Reinforcement Sensitivity Theory of Personality.
Alireza Kordbagheri, Rasha Mohamed Abdelrahman, Alaa F. Alsharif, Marei Ahmed   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Confirmatory Factor Analysis and Reliability of the Diabetes Treatment Satisfaction Questionnaire (DTSQ) for Arabic Speaking Patients with Type II Diabetes

Journal of Multidisciplinary Healthcare, 2020
Diana Arabiat,1,2 Lisa Whitehead,1,3 Buthina Abu Sheikh,4 Ebenezer Afrifa-Yamoah5 1Edith Cowan University, School of Nursing and Midwifery, Joondalup, Perth, WA 6027, Australia; 2Maternal and Child Nursing Department, The University of Jordan, Amman ...
Arabiat Snr D, Whitehead Snr L, Abu Sheikh Jnr B, Afrifa-Yamoah E   +3 more
doaj