Results 111 to 120 of about 8,165 (252)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Impact of News Coverage on Conflict: Toward Greater Understanding [PDF]

open access: yes, 2009
To be sure, the media and conflict have been studied from the perspective of a variety of mass media theories, including framing, critical discourse analysis, and others.
Reuben, Richard C.
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Freelancers on the Frontline: Influences on Conflict Coverage [PDF]

open access: yes, 2015
Some journalists who cover conflict in countries like Syria, Ukraine, and Egypt work as freelancers. As opposed to full-time staff members of media organizations, freelancers pay for their own travel, security, drivers, and insurance. While this model of
D\u27Arcy, Denae Lynn
core   +1 more source

German press coverage of former Yugoslavia after the fall of Miloševic [PDF]

open access: yesConflict & Communication Online, 2004
In the past few decades any war that received considerable attention in the Western public (like the wars in Vietnam, in the Gulf, in Bosnia, Kosovo, Afghanistan or Iraq) has been followed by numerous studies analyzing media coverage during the war.
Ute Annabring   +2 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Gender and Ethnicity in Post-Conflict Kosovo [PDF]

open access: yes
The paper examines the comparative economic wellbeing of female- and male-headed households among Serbs and Albanians in post-conflict Kosovo. Evidence from the living standards measurement study (LSMS) household survey, 2001, shows that Serb households,
Yun, Myeong-Su   +2 more
core  

High Stakes

open access: yesNordicom Review, 2016
Researchers are key sources of an increasing amount of research news in the media. Hitherto, the meagre empirical literature on researchers’ media performances has been divided in two strands: one indicating that researchers are generally motivated to ...
Carlsen Benedicte, Riese Hanne
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Peace Journalism through the Lense of Conflict Theory: Analysis and Practice [PDF]

open access: yesConflict & Communication Online, 2006
Peace Journalism is a bold attempt to redefine and reconstruct the role of journalists who cover conflicts. As a new arena of knowledge, Peace Journalism draws upon several theories and disciplines to enrich its validity and applicability. A major source
Samuel Peleg
doaj  

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