Results 141 to 150 of about 5,993,308 (366)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

On the origins of a Conflict of Interest in the Mutual Fund Industry [PDF]

open access: yes
Cet article traite des conflits d'intérêts existant entre les investisseurs et leur conseiller financier. Des contributions antérieures ont apporté des éclairages sur cette question en considérant soit les montants investis soit l'horizon d ...
Sébastien M. Lemeunier
core  

Post-Employment, “Revolving Door,” Laws for Federal Personnel [PDF]

open access: yes, 2012
[Excerpt] Conflict of interest regulations and restrictions on certain private employment opportunities for a federal officer or employee do not necessarily end with the termination of the officer’s or employee’s federal service.
Maskell, Jack
core   +2 more sources

Wrestling with `conflict of interest` in sport management

open access: yes, 2007
Purpose – The purpose of this paper is to discuss how the relationship between sport and business has increased the complexity of ethical issues affecting contemporary sport management.
Sherry, Emma   +2 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Failure to Disclose a Potential Conflict of Interest [PDF]

open access: bronze, 2019
Daniel E. Spratt   +3 more
openalex   +1 more source

State Litigation during the Obama Administration: Diverging Agendas in an Era of Polarized Politics [PDF]

open access: yes, 2014
Throughout the Obama Administration, state attorneys general (AGs) have collaborated on several high-profile political issues. To get a fuller picture of this contemporary AG activism, this article analyzes AG participation in lawsuits and amicus curiae ...
Nolette, Paul
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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