Results 41 to 50 of about 5,971,609 (331)

Mediation in Situations of Conflict and Limited Commitment [PDF]

open access: yes, 2004
We study the reasons and conditions under which mediation is beneficial when a principal needs information from an agent to implement an action. Assuming a strong form of limited commitment, the principal may employ a mediator who gathers information and
Mitusch, Kay, Strausz, Roland
core   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

STRESS TESTING IS AN IMPORTANT DIAGNOSTIC TOOL IN DETECTING CORONARY ARTERY DISEASE

open access: yesGomal Journal of Medical Sciences, 2015
Among many other causes of death, cardiovascular disease is the most common cause of death in developing countries including Pakistan. Management strategies for cardiovascular disease are constantly developing.
Muhammad Inam Qureshi   +3 more
doaj  

Human Resource Practices as Predictors of Work-Family Outcomes and Employee Turnover [PDF]

open access: yes, 2001
Drawing on a non-random sample of 557 dual- earner white collar employees, this paper explores the relationship between human resource practices and three outcomes of interest to firms and employees: work-family conflict, employees’ control over managing
Batt, Rosemary, Valcour, P. Monique
core   +2 more sources

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

Moral Pluralism and Conflict [PDF]

open access: yes, 2014
Institutions have often been characterized as responses to conflict, and assumptions about the nature of conflict have frequently determined the structure and scope of political activity.
Jason, Ferrell
core  

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

open access: yesFEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk   +3 more
wiley   +1 more source

Post-Employment, “Revolving Door,” Laws for Federal Personnel [PDF]

open access: yes, 2014
[Excerpt] Conflict of interest regulations and restrictions on certain private employment opportunities for a federal officer or employee do not necessarily end with the termination of the officer’s or employee’s federal service.
Maskell, Jack
core   +2 more sources

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