Results 41 to 50 of about 1,165,943 (351)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Education, Conflict and Harmony in Book 1 of Plato’s Laws

open access: yesRevista de Filosofia Antiga, 2021
Book 1 of Plato’s Laws, and particularly the image of the puppet introduced near its end, has been traditionally interpreted as presenting the moral psychology model that underlies the educational system delineated by the Athenian Stranger, which ...
Diego García Rincón
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Language in the Conflict of Laws: Qualification, Meaning of Concepts. The Case of Marriage

open access: yesStudies in Logic, Grammar and Rhetoric, 2019
According to E. G. Lorenzen, the international theory of the conflict of laws rests almost wholly on fiction. The discipline of conflict of laws is created by a huge number of national internal laws and quite a large number of international instruments ...
Bagan-Kurluta Katarzyna
doaj   +1 more source

Problèmes actuels en droit international privé congolais liés à l’abrogation de l’article 915 de la loi 87-010

open access: yesRecht in Afrika, 2018
The Congolese Code Civil Livre I (Civil Code Book I) was adopted in 1895. Although its material scope was confined to family law, it encompassed the most important conflict of laws provisions in Congolese private international law. When the new Congolese
Jean-Michel Kumbu Ki Ngimbi   +1 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The Conflict of Laws in Commercial Arbitration [PDF]

open access: yes, 1952
Most of the wastes in Sweden end up in incinerator plants. These trashes are full of metals, especially aluminium, which will not oxidize, they can’t always be recycled and they will instead oxidize in water and leak hydrogen gas to its surrounding ...
Stern, David S.
core   +2 more sources

Conflict of Laws in the Uniform Commercial Code [PDF]

open access: yes, 1951
Pulsatilla vernalis is one of several endangered plant species that benefit from wildfires and small scale disturbance events that repel competing vegetation and create open patches in the vegetation cover. Previous studies argue that Pulsatilla vernalis
Rheinstein, Max
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Interests and Policy Clashes in Conflict of Laws [PDF]

open access: yes, 1959
Glycoside hydrolases (GHs) cleave glycosidic bonds in glycoconjugates, oligosaccharides and polysaccharides such as cellulose and various hemicelluloses. Mannan is a major group of hemicelluloses.
Kramer, Robert
core   +2 more sources

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