Results 171 to 180 of about 1,248,632 (310)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Peace and Conflict Impact Assessment (PCIA) five years on the commodification of an idea (response paper) : Berghof handbook for conflict transformation

open access: yes, 2001
In the first “response article” to Mark Hoffman’s contribution in this Handbook, Ken Bush has taken a delightfully provocative stance. In critically addressing various points raised by Hoffman, it provides an opportunity to enter into the lively debates
Bush, Ken
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Rights Respecting Justice for Children in Conflict with the Law [PDF]

open access: yes
In 2021, in light of the commitment made by the Scottish Government to incorporate UNCRC into Scots Law, CYCJ convened a group of children’s rights experts from across England, Ireland, Jersey, Northern Ireland, Scotland and Wales to consider the ...
Vaswani, Nina   +7 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Do Giant Oilfield Discoveries Fuel Internal Armed Conflicts? [PDF]

open access: yes
We use new data to examine the effects of giant oilfield discoveries around the world since 1946. On average, these discoveries increase per capita oil production and oil exports by up to 50 percent.
Yu-Hsiang Lei, Guy Michaels
core  

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